Kim Sa Bu (Han Suk Kyu) was once a famous surgeon at the peak of his career at a major hospital. But he suddenly gives it all up one day to live in seclusion and work as a neighborhood doctor in a small town. He now goes by “Teacher Kim” and refers to himself as the “Romantic Doctor”.

Meanwhile, Kang Dong Joo (Yoo Yun Suk) became a doctor to make something of himself after growing up poor, and he seeks out VIP patients to achieve the success that he desperately wants. Yoon Seo Jung (Seo Hyun Jin) is a passionate young surgeon who is haunted by a mistake from her past and tries to get over it. When Dong Joo and Seo Jung meet the quirky Teacher Kim, their lives and careers will never be the same again.